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Prostaglandins promote and block adipogenesis through opposing effects on peroxisome proliferator-activated receptor gamma

Cellular swelling, karyolysis, karyorrhexis, vacuolization, release of cellular contents, endoplasmic reticulum stress, sterile inflammation, and autophagy are other mechanisms associated with APAP hepatotoxicity

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The uniqueness of this work lies in the highlighted benzimidazole scaffold hybridization with different molecules and benzimidazole-metal complexes, detailed mechanisms of action, and the IC 50 of the developed compounds determined by different laboratories after 2015